产品详情
Cat#:203P02
序列(三字母):H-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-OH trifluoroacetate salt
序列(单字母):SEVNLDAEF
类似名:(Asn⁶⁷⁰,Leu⁶⁷¹)-APP₇₇₀ (667-675), APP₇₇₀ (667-675) Swedish Mutation, (Asn670, Leu671)-Amyloid β/A4 Protein Precursor770 (667-675)
分子式:C₄₄H₆₆N₁₀O₁₈
分子量:1023.07
CAS#:150234-52-9
合成方法:Synthetic
存储条件:-20 ± 5 °C
应用:Alzheimer´s Disease
描述:SEVNLDAEF corresponds to the mutant junctional sequence of the amyloid precursor protein (APP) found in a Swedish family with early-onset Alzheimer´s disease, therefore referred to as the ´Swedish´ mutation (K670N/M671L). The peptide has been used for assaying cleavage at leucine-aspartate by cathepsin G and chymotrypsin, whereas neither cathepsin B, D nor L generated any products.
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