Cat#：203P08
序列（三字母）：H-Lys(Dabsyl)-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Arg-Gln-Lucifer Yellow ammonium salt
序列（单字母）：K(Dabsyl)-SEVNLDAEFRQ-Lucifer Yellow ammonium salt
类似名：Lys(Dabsyl)-(Asn⁶⁷⁰,Leu⁶⁷¹)-APP₇₇₀ (667-676)-Gln-Lucifer Yellow
分子式：C₈₉H₁₂₂N₂₄O₃₁S₃
分子量：2120.29
CAS#：1802078-42-7
合成方法：Synthetic
存储条件：-20 ± 5 °C
应用：Alzheimer´s Disease
描述：A highly selective substrate for measuring BACE1 (Km = 9 µM, kcat = 0.02 s⁻¹) and BACE2 activity. In this fluorescence resonance energy transfer (FRET) substrate the fluorescent group Lucifer Yellow is efficiently quenched by Dabsyl (4-(4-Dimethylaminophenylazo)benzenesulfonyl). Enzymatic cleavage can be assayed by detecting the increase in fluorescence emission at 520 nm using an excitation wavelength of 430 nm.