Cat#：205P18
序列（三字母）：H-Tyr-cyclo(-D-Dab-Arg-Phe-Phe-D-Trp-Lys-Thr-Phe) trifluoroacetate salt
序列（单字母）：Y-cyclo(-D-Dab-RFFwKTP)
类似名：KE 108
分子式：C₆₇H₈₅N₁₅O₁₁
分子量：1276.51
CAS#：496849-46-8
合成方法：Synthetic
存储条件：-20 ± 5 °C
应用：Cancer Research
描述：High affinity ligand for all five somatostatin receptors (sst1-sst5). In AtT-20 mouse anterior pituitary tumor cells which mainly express sst2 and sst5 receptors the binding affinity of this somatostatin analog was found to be higher than that of somatostatin-14 and octreotide. In a model of epileptogenesis, however, KE 108 did not exhibit antiepileptic activity suggesting that the high potency and efficacy of a synthetic ligand to all known somatostatin receptors may not reproduce entirely the effects of the natural ligand.