Cat#：217P163
序列（三字母）：H-Cys((RS)-2,3-di(palmitoyloxy)-propyl)-Gly-Asp-Pro-Lys-His-Pro-Lys-Ser-Phe-Asp-Tyr-Lys-Asp-Asp-Asp-Asp-Lys-OH trifluoroacetate salt
序列（单字母）：Pam₂CGDPKHPKSFDYKDDDDK
类似名：Fibroblast Stimulating Lipopeptide 1 FLAG-tag
分子式：C₁₂₅H₁₉₈N₂₄O₃₇S
分子量：2661.15
合成方法：Synthetic
存储条件：-20 ± 5 °C
应用：Immunomodulating Agents
描述：The lipopeptide FSL-1, synthesized on the basis of the N-terminal structure of a M. salivarium lipoprotein, is capable of inducing the cell surface expression of ICAM-1 in human gingival fibroblasts. It furthermore revealed an activity to induce production of monocyte chemoattractant protein 1, interleukin-6 (IL-6), and IL-8. FSL-1 also activated macrophages to produce tumor necrosis factor alpha. Overall, results by Okusawa and coworkers suggest that the diacylglyceryl and the peptide portions of FSL-1 are indispensable for the expression of biological activities and for the recognition by Toll-like receptors 2 and 6. Furthermore, the same authors conclude that the recognition of FSL-1 by Toll-like receptors 2 and 6 apparently is hydrophobic.