Cat#: 112P17
序列（三字母）：H-Ala-Thr-Cys-Tyr-Cys-Arg-Thr-Gly-Arg-Cys-Ala-Thr-Arg-Glu-Ser-Leu-Ser-Gly-Val-Cys-Glu-Ile-Ser-Gly-Arg-Leu-Tyr-Arg-Leu-Cys-Cys-Arg-OH(Disulfide bonds, air oxidized)
序列（单字母）：ATCYCRTGRCATRESLSGVCEISGRLYRLCCR
类似名：Defensin HD 5, HD 5, Human α-defensin 5, α-Defensin 5 (human)
分子式：C₁₄₄H₂₃₈N₅₀O₄₅S₆
分子量：3582.18
合成方法：固相合成
存储条件：-20 ± 5 °C，避光，干燥
应用：Antimicrobial & Antiviral Peptides
描述：Human defensin-5 (HD 5) is a key regulator of gut microbiota homeostasis. HD 5 exhibits microbicidal activity against bacteria, fungi, and viruses and is released by Paneth cells in the small intestine. Reduction or absence of HD 5 release in the intestinal mucosa has been associated with susceptibility to enteric pathogens, changes in composition of the microbiota, and disruption of intestinal immune homeostasis. As a biomarker, HD 5 might be used to distinguish between ulcerative colitis (low levels of HD 5) or Crohn´s colitis (high levels of HD 5).