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112P24

Dermcidin-1L (human)

H-Ser-Ser-Leu-Leu-Glu-Lys-Gly-Leu-Asp-Gly-Ala-Lys-Lys-Ala-Val-Gly-Gly-Leu-Gly-Lys-Leu-Gly-Lys-Asp-Ala-Val-Glu-Asp-Leu-Glu-Ser-Val-Gly-Lys-Gly-Ala-Val-His-Asp-Val-Lys-Asp-Val-Leu-Asp-Ser-Val-Leu-OH

纯度:>95%HPLC
储存条价:-20 ± 5 °C,避光,干燥。

另提供从粗品至98%纯度规格,具体请联系我们!
本产品仅用于科学研究,不得用于人体!




产品详情

Cat#: 112P24
序列(三字母):H-Ser-Ser-Leu-Leu-Glu-Lys-Gly-Leu-Asp-Gly-Ala-Lys-Lys-Ala-Val-Gly-Gly-Leu-Gly-Lys-Leu-Gly-Lys-Asp-Ala-Val-Glu-Asp-Leu-Glu-Ser-Val-Gly-Lys-Gly-Ala-Val-His-Asp-Val-Lys-Asp-Val-Leu-Asp-Ser-Val-Leu-OH
序列(单字母):SSLLEKGLDGAKKAVGGLGKLGKDAVEDLESVGKGAVHDVKDVLDSVL
类似名:DCD-1L (human)
分子式:C₂₁₀H₃₅₉N₅₇O₇₁
分子量:4818.5
CAS#:478898-18-9
合成方法:固相合成
存储条件:-20 ± 5 °C,避光,干燥
应用:Antimicrobial & Antiviral Peptides| Cosmetic Peptides & Dermatology
描述:The protein dermcidin expressed in the sweat glands is secreted into the sweat and transported to the epidermal surface. The concomitant processing of the protein yields a broad-spectrum antimicrobial 47 amino acid peptide, dermcidin-1 (DCD-1). Dermcidin and naturally occurring fragments as DCD-1L do not perturb membrane permeability and bind to distinct surface molecules. Niyonsaba et al. have reported that DCD-1L stimulates keratinocytes to generate cytokines and chemokines such as TNF-α, IL-8, CXCL10, and CCL20.




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