Cat#: 121P08
序列（三字母）：(5S)-1-[(2S)-O-(N,N-Dimethyl-Val-Val-N-Me-Val-Pro-Pro)-2-hydroxyisovaleryl]-2-oxo-4-methoxy-5-benzyl-3-pyrroline
分子式：C₄₅H₆₈N₆O₉
分子量：837.07
CAS#：123884-00-4
合成方法：固相合成
存储条件：-20 ± 5 °C，避光，干燥
应用：Apoptosis & Necrosis| Cancer Research
描述：Dolastatin 15 originally isolated from the sea hare Dolabella auricularia belongs to a family of antimitotic and antineoplastic depsipeptides inducing apoptosis in various malignant cell types. It was shown to inhibit the growth of the P388 lymphocytic leukemia cell line efficiently, with an ED₅₀ value of 2.4 ng/mL.