Cat#: 123P25
序列（三字母）：Ac-Trp-Glu-His-Asp-AMC
序列（单字母）：Ac-WEHD-AMC
类似名：Ac-WEHD-AMC
分子式：C₃₈H₄₀N₈O₁₁
分子量：784.78
CAS#：189275-74-9
合成方法：Synthetic
存储条件：-20 ± 5 °C
应用：Apoptosis & Necrosis
描述：With a kcat/Km of 3.3 · 10⁶ M⁻¹s⁻¹ the fluorogenic caspase-1 substrate Ac-WEHD-AMC is cleaved 50-fold more efficiently. This result indicates that the optimal tetrapeptide recognition sequence for caspase-1 is Trp-Glu-His-Asp and not Tyr-Val-Ala-Asp.