Cat#: 123P39
序列（三字母）：H-Asn-Glu-Ala-Tyr-Val-His-Asp-Ala-Pro-Val-Arg-Ser-Leu-Asn-OH
序列（单字母）：NEAYVHDAPVRSLN
类似名：H-NEAYVHDAPVRSLN-OH, N-E-A-Y-V-H-D-A-P-V-R-S-L-N
分子式：C₆₈H₁₀₅N₂₁O₂₃
分子量：1584.71
CAS#：143305-11-7
合成方法：Synthetic
存储条件：-20 ± 5 °C
应用：Apoptosis & Necrosis
描述：IL-1β converting enzyme (ICE, now called caspase-1), a cytosolic enzyme, is responsible for the cleavage of the inactive precursor protein to the active IL-1β. Similarly, caspase-1 hydrolyzes this 14-amino acid peptide that corresponds to the native cleavage site sequence around Asp¹¹⁶-Ala¹¹⁷. The peptide is also able to inhibit the cleavage of the precursor to the mature protein.