Cat#: 123P54
序列（三字母）：DABCYL-Tyr-Val-Ala-Asp-Ala-Pro-Val-EDANS trifluoroacetate salt
序列（单字母）：DABCYL- YVADAPV -EDANS
类似名：DABCYL-YVADAPV-EDANS
分子式：C₆₁H₇₆N₁₂O₁₄S
分子量：1233.41
CAS#：161877-70-9
合成方法：Synthetic
存储条件：-20 ± 5 °C
应用：Apoptosis & Necrosis
描述：The fluorogenic caspase-1 (ICE) substrate Dabcyl-YVADAPV-Edans is based on the principle of resonance energy transfer. It allows a continuous assay of caspase-1 that is useful in the screening of inhibitory compounds (Km = 11.4 µM, kcat = 0.79 s⁻¹). Enzymatic cleavage of the FRET substrate yields DABCYL-YVAD and APV-EDANS M-2030.