Cat#：137P13
序列（三字母）：Cyclo(-Gly-Asn-Trp-His-Gly-Thr-Ala-Pro-Asp)-Trp-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-Ile-Trp-OH
序列（单字母）：c(GNWHGTAPD)WVYFAHLDIIW
分子式：C₁₁₇H₁₅₀N₂₈O₂₇
分子量：2380.65
CAS#：151308-48-4
合成方法：Synthetic
存储条件：-20 ± 5 °C
应用：Cardiovascular System & Diseases
描述：The C-terminal sequence of this hybrid peptide corresponds to (Ala¹⁵)ET-1 (12-21), and the N-terminal sequence is derived from RES-701-1, an endothelin type B (ET-B) receptor antagonist of microbial origin. This hybrid peptide showed a selectivity for the type B receptor and inhibited ET-1 binding to ET-B receptor with an IC₅₀ value of 0.24 nM.