产品详情
Cat#:139P36
序列(三字母):L-trans-Epoxysuccinyl-Ile-Pro-OMe propylamide
序列(单字母):L-trans-Epoxysuccinyl-IP-OMe
类似名:CA-074Me, L-trans-Epoxysuccinyl(propylamide)-Ile-Pro-OMe, N-(L-3-trans-(Propylamino)carbonyl)-oxirane-2-carbonyl)-Ile-Pro-OMe
分子式:C₁₉H₃₁N₃O₆
分子量:397.47
CAS#:147859-80-1
合成方法:Synthetic
存储条件:-20 ± 5 °C
描述:CA-074Me, the membrane-permeant prodrug of CA-074, represents a proinhibitor, that itself is almost inactive, but can enter cells and there inhibit intracellular cathepsin B. Therefore CA-074Me is suggested to be a very promising reagent for the investigation of the intracellular functions of cathepsin B. This cysteine protease showing β-secretase activity could be involved in amyloid β formation.
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