Cat#：140P88
序列（三字母）：Boc-Val-Pro-Arg-AMC hydrochloride salt
序列（单字母）：Boc-VPR-AMC
分子式：C₃₁H₄₅N₇O₇
分子量：627.74
CAS#：65147-04-8
合成方法：Synthetic
存储条件：-20 ± 5 °C
应用：Hematology
描述：Boc-VPR-AMC, a specific, highly fluorogenic substrate for thrombin and the thrombin-staphylocoagulase complex. The thrombin assay has been used for the indirect determination of coagulation factor III. Trypsin, tryptase from rat mast cells, and two trypsin-like enzymes from sperm of the ascidian Halocynthia roretzi, acrosin and spermosin, also hydrolyze this substrate. Furthermore, Boc-VPR-AMC is cleaved by the Kex2 endoprotease (kexin, previously known as proteinase yscF), a membrane-bound, calcium-dependent serine protease from yeast α-cells.