Cat#：140P193
序列（三字母）：Mca-Gly-Ser-Pro-Ala-Phe-Leu-Ala-Lys(Dnp)-D-Arg-NH₂ trifluoroacetate salt
序列（单字母）：Mca-GSPAFLAK(Dnp)-r-NH₂
分子式：C₆₁H₈₂N₁₆O₁₈
分子量：1327.42
CAS#：592544-81-5
合成方法：Synthetic
存储条件：-20 ± 5 °C
应用：Cancer Research| Hematology
描述：Highly sensitive and selective cathepsin E FRET substrate derived from the cleavage site sequence of human α2-macroglobulin (Km = 1.9 µM; kcat/Km = 10.2 µM⁻¹s⁻¹ for human erythrocyte cathepsin E). The substrate was resistent to hydrolysis by the analogous aspartic proteinases cathepsin D and pepsin, as well as the lysosomal cysteine proteinases cathepsin B, L, and H. Useful for monitoring and accurately quantifying cathepsin E, even in crude enzyme preparations (excitation wavelength at 328 nm, emission wavelength at 393 nm).