产品详情
Cat#:140P206
序列(三字母):4-Nitro-Z-Gly-Cys(7-nitro-benzo[2,1,3]oxadiazol-4-yl)-Gly-OH
序列(单字母):p-Nitro-Z- GC(NBD)G
类似名:4-Nitro-Z-Gly-Cys(NBD)-Gly-OH, 4-Nitro-Z-Gly-Cys(7-nitrobenzofurazan-4-yl)-Gly-OH
分子式:C₂₁H₁₉N₇O₁₁S
分子量:577.49
CAS#:152390-46-0
合成方法:Synthetic
存储条件:-20 ± 5 °C
应用:Cardiovascular System & Diseases
描述:Substrate for angiotensin I-converting enzyme (ACE) containing the green fluorophore NBD, which is shifted from S to N after enzymatic cleavage (4,4´-dithiopyridine is added to the assay to scavenge the liberated sulfhydryl group). This rearrangement causes a shift of the absorption maximum from 423 to 461 nm. Cleavage of the substrate is best monitored by measuring the increase of absorption at 470 nm.
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