Cat#：140P277
序列（三字母）：Suc-Leu-Leu-Val-Tyr-AMC
序列（单字母）：Suc-LLVY-AMC
类似名：Chymotrypsin Substrate III, Fluorogenic
分子式：C₄₀H₅₃N₅O₁₀
分子量：763.89
CAS#：94367-21-2
合成方法：Synthetic
存储条件：-20 ± 5 °C
描述：The fluorogenic substrate Suc-LLVY-AMC is used for measuring the chymotrypsin-like activity of the 20S proteasome, in combination with e.g. Bz-VGR-AMC (for assaying its trypsin-like activity) and Z-LLE-AMC (for determining its PGPH activity). Suc-LLVY-AMC is also cleaved by a chymotrypsin-like enzyme from sperm extract of the ascidian Halocynthia roretzi, a strong inhibitor of fertilization. The substrate has also been used to analyze the chymotrypsin-like activity of trypsins as well as chymase from rat mast cells. Furthermore, Suc-LLVY-AMC is a substrate for carboxypeptidase Y, proteinase yscE (kexin), ingensin, as well as for porcine calpain isozymes I and II and for papain.