Cat#：140P339
序列（三字母）：Z-His-Phe-Phe-OEt
序列（单字母）：Z-HFF-OEt
分子式：C₃₄H₃₇N₅O₆
分子量：611.7
CAS#：13053-61-7
合成方法：Synthetic
存储条件：-20 ± 5 °C
描述：zHFFe, a good substrate for pepsin. Hertel et al identified zHFFe as a potent inhibitor of zero-trans glucose flux with a Ki of 26 μM. Similar to HIV protease inhibitors, transport inhibition by this peptide was acute, non-competitive, and reversible. Within a Xenopus oocyte expression system, zHFFe acutely and reversibly inhibited GLUT4-mediated glucose uptake, whereas GLUT1 activity was unaffected at concentrations as high as 1 mM.