Cat#：143P29
序列（三字母）：Cyclo(-D-Tyr-Arg-Gly-Asp-Cys(carboxymethyl)-OH) sulfoxide
序列（单字母）：Cyclo(-yRGDC(carboxymethyl)-OH)
分子式：C₂₆H₃₆N₈O₁₁S
分子量：668.69
CAS#：143120-27-8
合成方法：Synthetic
存储条件：-20 ± 5 °C
应用：Adhesion Molecules & Extracellular Matrix Proteins| Hematology| Regenerative Medicine
描述：This sulfur-bridged cyclic RGD peptide is a potent inhibitor of the binding of glycoprotein IIb/IIIa to fibrinogen with an IC₅₀ of 1.5 nM. Furthermore, it is a highly potent inhibitor of fibrinogen-mediated platelet aggregation (IC₅₀ = 0.15 µM). Its antithrombotic activity in vivo may render this compound useful in the treatment of arterial thromboembolic diseases.