Cat#：143P32
序列（三字母）：H-Glu-Cys-Glu-Ser-Gly-Pro-Cys-Cys-Arg-Asn-Cys-Lys-Phe-Leu -Lys-Glu-Gly-Thr-Ile-Cys-Lys-Arg-Ala-Arg-Gly-Asp-Asp-Met- Asp-Asp-Tyr-Cys-Asn-Gly-Lys-Thr-Cys-Asp-Cys-Pro-Arg-Asn- Pro-His-Lys-Gly-Pro-Ala-Thr-OH (Disulfide bonds between Cys² and Cys¹¹/Cys⁷ and Cys³²/Cys⁸ and Cys³⁷/Cys²⁰ and Cys³⁹)
序列（单字母）：ECESGPCCRNCKFLKEGTICKRARGDDMDDYCNGKTCDCPR NPHKGPAT
分子式：C₂₁₇H₃₄₁N₇₁O₇₄S₉
分子量：5417.12
CAS#：154303-05-6
合成方法：Synthetic
存储条件：-20 ± 5 °C
应用：Hematology| Osteoporosis Research
描述：Echistatin is a 49-amino acid polypeptide from the venom of the saw-scaled viper, Echis carinatus. The peptide containing an RGD motif binds to the glycoprotein IIb/IIIa receptor on the platelet and is a potent competitive inhibitor of ADPstimulated platelet aggregation mediated by fibrinogen and other factors. Furthermore, echistatin effectively inhibits osteoclastic bone resorption in vitro and in vivo.