Cat#：143P37
序列（三字母）：(4-((2-Methylphenyl)aminocarbonyl)-aminophenyl)acetyl-Leu-Asp-Val-Pro-OH
序列（单字母）：(4-((2-Methylphenyl)aminocarbonyl)-aminophenyl)acetyl-LDVP
分子式：C₃₆H₄₈N₆O₉
分子量：708.81
CAS#：187735-94-0
合成方法：Synthetic
存储条件：-20 ± 5 °C
应用：Adhesion Molecules & Extracellular Matrix Proteins
描述：The VLA-4 inhibitor BIO-1211 based on the LDVP motif represents a selective, tight-binding inhibitor of integrin α₄β₁ achieved by appending an optimal organic group to the N-terminus of the peptide (Kd = 70 pM). Moreover, this inhibitor exhibited > 200-fold selectivity for the activated form of the integrin α₄β₁ receptor.