Cat#：146P04
序列（三字母）：H-Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-His-Ala-Ile-Asp-Asn-His-Arg-Ser-Phe-Ser-Asp-Lys-His-Gly-Leu-Thr-NH₂
序列（单字母）：GWTLNSAGYLLGPHAIDNHRSFSDKHGLT-NH₂
分子式：C₁₄₁H₂₁₁N₄₃O₄₁
分子量：3164.49
CAS#：114547-31-8
合成方法：Synthetic
存储条件：-20 ± 5 °C
应用：Alzheimer´s Disease
描述：The isolation and characterization of cDNAs encoding rat galanin and its precursor peptide reveal that rat galanin is synthesized initially as part of a 124-amino acid precursor that includes a signal peptide, galanin, and a 60-amino acid galanin mRNA-associated peptide. The neuropeptide galanin shows multiple inhibitory actions on neurotransmission and memory. In Alzheimer´s disease, increased galanin-containing fibers hyperinnervate cholinergic neurons within the basal forebrain in association with a decline in cognition.