产品详情
Cat#:146P11
序列(三字母):H-Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH₂
序列(单字母):GWTLNSAGYLLGPQQFFGLM-NH₂
类似名:Galantide, M15
分子式:C₁₀₄H₁₅₁N₂₅O₁₆S
分子量:2199.56
CAS#:138579-66-5
合成方法:Synthetic
存储条件:-20 ± 5 °C
描述:The chimaeric peptide galantide is a high-affinity ligand for galanin receptors in membranes from rat hypothalamus, hippocampus, and spinal cord. There it reversibly blocks the neuronal actions of galanin in a dose-dependent manner. The peptide also reverses the galanin-mediated inhibition of insulin release from mouse pancreatic islets. Antagonists such as galantide are therefore of potential importance both as therapeutic agents and in studies on the physiological roles of galanin.
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