Cat#：153P09
序列（三字母）：H-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH₂ trifluoroacetate salt
序列（单字母）：EGTFTSDVSSYLEGQAAKEFIAWLVKGR-NH₂
类似名：Glucagon-Like Peptide 1 (9-36) amide (human, bovine, guinea pig, mouse, porcine, rat), Preproglucagon (100-127) amide (human, bovine, guinea pig, mouse, porcine, rat), Proglucagon (80-107) amide (human, bovine, guinea pig, mouse, porcine, rat)
分子式：C₁₄₀H₂₁₄N₃₆O₄₃
分子量：3089.46
CAS#：161748-29-4
合成方法：Synthetic
存储条件：-20 ± 5 °C
应用：Diabetes
描述：Glucagon-like peptide-1 (GLP-1) is efficiently degraded by the enzyme dipeptidyl peptidase IV (DPP IV), yielding the major metabolite GLP-1 (9-36) amide. GLP-1 (9-36) amide does not affect glucose disposal in mice either in the presence or absence of intact GLP-1 receptors or in the presence or absence of stimulated insulin levels. This suggests that the GLP-1 metabolite is not involved in the regulation of glucose homeostasis. Elahi et al. have shown that this GLP-1 metabolite acts as a weak insulinotropic agent and inhibits hepatic glucose production.