Cat#：153P13
序列（三字母）：H-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-OH
序列（单字母）：HSQGTFTSDYSKYLDSRRAQDFVQWLMNT
类似名：Glucagon, human
分子式：C₁₅₃H₂₂₅N₄₃O₄₉S
分子量：3482.8
CAS#：16941-32-5
合成方法：Synthetic
存储条件：-20 ± 5 °C
应用：Diabetes| Veterinary Medicine
描述：Glucagon is a 29 amino acid containing peptide hormone processed from proglucagon. As a counterregulatory hormone for insulin, glucagon plays a critical role in maintaining glucose homeostasis in vivo in both animals and humans. Not surprisingly, glucagon and glucagon receptor have been pursued extensively as potential targets for the therapeutic treatment of diabetes. As Aβ peptides and IAPP, glucacon tends to form gel-like fibrillar aggregates. These fibrils were found to be toxic through the activation of apoptotic signaling pathways. Hence the aggregation behavior of glucagon has been studied extensively.