Cat#：173P08
序列（三字母）：DABCYL-γ-Abu-Pro-Gln-Gly-Leu-Glu(EDANS)-Ala-Lys-NH₂
序列（单字母）：DABCYL-γ-Abu-PQGLE(EDANS)AK-NH₂
类似名：MMP Substrate III, Fluorogenic
分子式：C₆₃H₈₈N₁₆O₁₄S
分子量：1325.56
CAS#：193475-71-7
合成方法：Synthetic
存储条件：-20 ± 5 °C
应用：Cancer Research| Inflammation Research
描述：Highly soluble fluorogenic (FRET) matrix metalloproteinase (MMP) substrate with the following kcat/Km values (at pH 7.6, 37 °C): 619.000 M⁻¹s⁻¹ for MMP-2, 209.000 M⁻¹s⁻¹ for MMP-9, 40.000 M⁻¹s⁻¹ for MMP-3, and 21.000 M⁻¹s⁻¹ for MMP-1. The fluorescence increase is measured using an excitation wavelength of 340 nm and an emission wavelength of 485 nm. Due to the relatively high emission wavelength of EDANS the substrate allows convenient measurement of MMP activity in complex biological media like synovial fluid and culture medium.