Cat#：173P18
序列（三字母）：Mca-Pro-β-cyclohexyl-Ala-Gly-Nva-His-Ala-Dap(Dnp)-NH₂ trifluoroacetate salt
序列（单字母）：Mca-P-Cha-AG-Nva-HA-Dpa-NH₂
类似名：MMP-13 Substrate, Fluorogenic
分子式：C₅₁H₆₅N₁₃O₁₅
分子量：1100.16
CAS#：256394-94-2
合成方法：Synthetic
存储条件：-20 ± 5 °C
应用：Cancer Research| Inflammation Research
描述：Specific fluorogenic (FRET) substrate for collagenase-3 (MMP-13) with a kcat/Km value of 1.09 · 10⁶ M⁻¹s⁻¹ (pH = 7.5, T = 25 °C, substrate concentrations: 0.7 and 1.4 µM (S << Km), determined for activated recombinant collagenase-3). Collagenase-3 hydrolyzed Mca-Pro-Cha-Gly-Nva-His-Ala-Dpa-amide 70 - 100 fold more efficiently than collagenase-2 (MMP-8) and collagenase-1 (MMP-1).