Cat#：174P11
序列（三字母）：Ac-Nle-cyclo(-Asp-His-D-Phe-Arg-Trp-Lys-NH₂) acetate salt
序列（单字母）：Ac-Nle-cyclo(-DHfRWK-NH₂)
类似名：MTII, Melanotan II, Bremelanotide amide, (Ac-Nle4, Asp5, DPhe7, Lys10)-Cyclo-a-MSH (4-10) amide
分子式：C₅₀H₆₉N₁₅O₉
分子量：1024.19
CAS#：121062-08-6
合成方法：Synthetic
存储条件：-20 ± 5 °C
应用：Cancer Research| Cosmetic Peptides & Dermatology| Obesity Research| Pituitary & Hypothalamic Hormones
描述：Melanotan II, a cyclic MSH analog, is a potent full agonist of the melanocortin-3 and melanocortin-4 receptors (MC3-R and MC4-R). Intracerebroventricular administration of MTII inhibited feeding in four different mouse models of hyperphagia. MTII is a valuable tool for the study of the agouti obesity syndrome and of the role of melanocortinergic neurons in feeding.