Cat#：186P09
序列（三字母）：H-Tyr-Pro-Phe-Pro-Gly-Pro-Ile-OH
序列（单字母）：YPFPGPI
类似名：β-Casomorphin-7 (bovine), β-Casomorphin (1-7), bovine
分子式：C₄₁H₅₅N₇O₉
分子量：789.93
CAS#：72122-62-4
合成方法：Synthetic
存储条件：-20 ± 5 °C
应用：Opioid Research
描述：BCM-7, YPFPGPI, has first been isolated from an enzymatic casein digest. Only cow casein variants A1 and B yield this bioactive peptide after in vitro digestion with intestinal enzymes, but not the common A2 variant. β-Casomorphin displays opioid properties. The β-casomorphin generated by digestion of bovine milk could play a role in the aetiology of human diseases as type 1 diabetes and cardiovascular affections. In a rat model, BCM-7 attenuated the development of nephropathy in type I diabetes via inhibition of epithelial-mesenchymal transition of renal tubular epithelial cells.