Cat#：157P05
序列（三字母）：H-Asn-Asp-Asp-Cys-Glu-Leu-Cys-Val-Asn-Val-Ala-Cys-Thr-Gly-Cys-Leu-OH trifluoroacetate salt(Disulfide bonds between Cys⁴ and Cys¹²/Cys⁷ and Cys¹⁵)
序列（单字母）：NDDCELCVNVACTGCL
类似名：UGN Topoisomer B (human)
分子式：C₆₄H₁₀₂N₁₈O₂₆S₄
分子量：1667.88
合成方法：Synthetic
存储条件：-20 ± 5 °C
应用：Gastrointestinal Research| Obesity Research
描述：Short peptides containing two disulfide bridges can form interconvertible topoisomers with the same disulfide connectivity. In case of uroguanylin (UGN), both are relatively stable and can be separated, and interconversion is slow. The topoisomers differ in biological activity: The UGN A topomer potently activates the guanylate cyclase C receptor found primarily in the intestine. The B topomer is a very weak agonist of this receptor. Moss et al. could show that UGN B has potent natriuretic activity in the kidney.