产品详情
Cat#:168P07
序列(三字母):H-Tyr-Ile-Gly-Ser-Arg-OH trifluoroacetate salt
序列(单字母):YIGSR
类似名:Laminin β-1 Chain (929-933) (human, mouse), YIGSR, Laminin Fragment (929-933)
分子式:C₂₆H₄₂N₈O₈
分子量:594.67
CAS#:110590-64-2
合成方法:Synthetic
存储条件:-20 ± 5 °C
应用:Adhesion Molecules & Extracellular Matrix Proteins|
Cancer Research|
Cell Culture|
Regenerative Medicine
描述:The pentapeptide YIGSR located within domain III of the laminin B1 chain, represents a major receptor binding site in laminin. By competing with laminin for the cell surface receptor, the short peptide is able to inhibit cell attachment to basement membranes, thus preventing the formation of tumor metastases. YIGSR also promotes tumor cell migration and, moreover, mediates the adhesion of a variety of epithelial cells to laminin.
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