Cat#：173P25
序列（三字母）：6-(7-Nitro-benzo[2,1,3]oxadiazol-4-ylamino)-hexanoyl-Arg-Pro-Lys-Pro-Leu-Ala-Nva-Trp-Lys((7-dimethylaminocoumarin-4-yl)-acetyl)-NH₂ trifluoroacetate salt
序列（单字母）：NBD-ε-aminocaproyl-RPKPLA-Nva-WK(DMACA)-NH₂
类似名：NBD-ε-aminocaproyl-Arg-Pro-Lys-Pro-Leu-Ala-Nva-Trp-Lys(DMACA)-NH₂
分子式：C₇₈H₁₁₁N₂₁O₁₆
分子量：1598.87
CAS#：945414-97-1
合成方法：Synthetic
存储条件：-20 ± 5 °C
应用：Cancer Research| Inflammation Research
描述：NBD-Arg-Pro-Lys-Pro-Leu-Ala-Nva-Trp-Lys(DMC)-NH₂ (NBD-RPKPLA-Nva-WK(DMC) amide) is an excellent fluorogenic substrate for hydrolysis of the matrix metalloproteinase stromelysin (MMP-3). This FRET substrate exhibits high sensitivity and improves accuracy at lower substrate turnover. It has a kcat/Km value of 2.14 x 10⁴ M⁻¹s⁻¹ and can be easily detected at 350 nm (excitation) and 465 nm (emission). Therefore this compound is a suitable tool for high-throughput inhibitor screening.