Cat#：174P21
序列（三字母）：Ac-D-Arg-Cys-Glu-His-D-Phe-Arg-Trp-Cys-NH₂ trifluoroacetate salt(Disulfide bond)
序列（单字母）：Ac-rCEHfRWC-NH₂
分子式：C₅₁H₇₀N₁₈O₁₁S₂
分子量：1175.36
CAS#：819048-44-7
合成方法：Synthetic
存储条件：-20 ± 5 °C
应用：Obesity Research| Pituitary & Hypothalamic Hormones
描述：Highly potent and selective β-MSH-derived melanocortin-4 receptor (MC-4R) agonist with sub-nanomolar potency. The binding affinities for human MC-4R, MC-1R, MC-3R and MC-5R were 0.55 ± 0.06, 16.78 ± 1.53, 56.79 ± 4.66, and < 500 nM, respectively. Daily subcutaneous injection of this product to diet-induced obese rats over a period of 14 days demonstrated an effect on reduction of fat mass.