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181P29

(Gly¹,Ser³·²²,Gln⁴·³⁴,Thr⁶,Arg¹⁹,Tyr²¹,Ala²³·³¹,Aib³²)-Pancreatic Polypeptide (human) trifluoroacetate salt

H-Gly-Pro-Ser-Gln-Pro-Thr-Tyr-Pro-Gly-Asp-Asn-Ala-Thr-Pro-Glu-Gln-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-Arg-Tyr-Ile-Asn-Met-Ala-Aib-Arg-Gln-Arg-Tyr-NH₂ trifluoroacetate salt

纯度:>95%HPLC
储存条价:-20 ± 5 °C,避光,干燥。

另提供从粗品至98%纯度规格,具体请联系我们!
本产品仅用于科学研究,不得用于人体!


产品详情

Cat#:181P29
序列(三字母):H-Gly-Pro-Ser-Gln-Pro-Thr-Tyr-Pro-Gly-Asp-Asn-Ala-Thr-Pro-Glu-Gln-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-Arg-Tyr-Ile-Asn-Met-Ala-Aib-Arg-Gln-Arg-Tyr-NH₂ trifluoroacetate salt
序列(单字母):GPSQPTYPGDNATPEQMARYYSALRRYINMA-Aib-YQYR-NH₂
类似名:(Gly¹,Gln⁴·¹⁶,Thr⁶·¹³,Tyr⁷,Asp¹⁰,Asn¹¹,Pro¹⁴,Arg²⁶,Met³⁰,Ala³¹,Aib³²)-Neuropeptide Y (human, rat)
分子式:C₁₈₃H₂₈₁N₅₇O₅₄S₂
分子量:4207.73
CAS#:313988-89-5
合成方法:Synthetic
存储条件:-20 ± 5 °C
应用:Obesity Research
描述:This (Ala-Aib)-containing pancreatic peptide/neuropeptide Y chimera is a highly selective neuropeptide Y₅ receptor agonist. At this receptor this compound turned out to be 25-fold more potent than the derivative H-5084 (0.24 nM vs 6 nM) and three-fold more potent than the native ligand neuropeptide Y (H-6375) (0.24 nM vs 0.6 nM). This analog turned out to increase feeding approximately 2.5-fold more effective than neuropeptide Y.


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