产品详情
Cat#:186P35
序列(三字母):H-Tyr-L-1,2,3,4-tetrahydroisoquinoline-3-carboxamide · HCl
序列(单字母):Y-L-1,2,3,4-tetrahydroisoquinoline-3-carboxamide · HCl
类似名:H-Tyr-Tic-NH₂ · HCl
分子式:C₁₉H₂₁N₃O₃ · HCl
分子量:375.86
CAS#:154121-70-7
合成方法:Synthetic
存储条件:-20 ± 5 °C
应用:Di- and Tripeptides
描述:Tyr-Tic-amide and its epimer are the first example for opioid peptides consisting of a message domain of only two residues. In addition, they are the first opioid dipeptides with significant opioid activity and represent a first meaningful link among peptide opioids and alkaloid opiates and thus may form the basis for an unified receptor site model. It has been shown furthermore that peptides containing the Tyr-Tic motif , as TIPP, act as very selective antagonists for δ-opioid receptors and those containing Tyr-D-Tic as non-selective μ-agonists.
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