Cat#：201P08
序列（三字母）：DABCYL-γ-Abu-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-EDANS trifluoroacetate salt
序列（单字母）：DABCYL-Abu-HPFHLVIHT-EDANS
分子式：C₉₀H₁₂₀N₂₂O₁₆S
分子量：1798.15
CAS#：142988-22-5
合成方法：Synthetic
存储条件：-20 ± 5 °C
应用：Cardiovascular System & Diseases
描述：The fluorogenic peptide substrate DABCYL-Abu-HPFHLVIHT-EDANS has been developed to continuously measure the proteolytic activity of human renin (Km = 1.5 µM at physiological pH). Cleavage of the FRET substrate occurs specifically at the Leu-Val bond and corresponds to the renin cleavage site of angiotensinogen. By means of this assay as low as 30 ng/mL renin can be detected after an incubation of only 3-5 min.