Cat#：203P18
序列（三字母）：H-Glu-Leu-Asp-[(2R,4S,5S)-5-amino-4-hydroxy-2,7-dimethyl-octanoyl]-Ala-Glu-Phe-OH
序列（单字母）：ELD[(2R,4S,5S)-5-amino-4-hydroxy-2,7-dimethyl-octanoyl]AEF
分子式：C₄₂H₆₅N₇O₁₅
分子量：908.02
CAS#：1349991-28-1
合成方法：Synthetic
存储条件：-20 ± 5 °C
应用：Alzheimer´s Disease
描述：Glu-Leu-Asp-Leu-psi[CHOH-CH₂]-Ala-Ala-Glu-Phe (ELDL-psi[CHOH-CH₂]-AAEF), a potent inhibitor for human brain memapsin-2 (β-secretase) with a Ki-value of 0.3 nM. The hydroxyethylene isostere of the Leu-Ala motif functions as a mimic of the transition state.