Cat#：203P22
序列（三字母）：Z-Leu-Leu-4,5-dehydro-Leu-aldehyde
序列（单字母）：Z-LL-4,5-dehydro-L-aldehyde
类似名：SIB 1281, Z-Leu-Leu-4,5-dehydro-Leu-CHO
分子式：C₂₆H₃₉N₃O₅
分子量：473.61
CAS#：181139-85-5
合成方法：Synthetic
存储条件：-20 ± 5 °C
应用：Alzheimer´s Disease
描述：The peptide aldehyde SIB1281 inhibited the formation of β- and γ-secretase derived amyloid β-protein (Aβ) with IC₅₀ = 1.8 µM and stimulated the formation of α-secretase derived soluble amyloid precursor protein (sα) with an EC₅₀ of 250 nM.