Cat#: 107P139
序列（三字母）：H-Glu-Gln-Val-Thr-Asn-Val-Gly-Gly-Ala-Val-Val-Thr-Gly-Val-Thr-Ala-Val-Ala-Gln-Lys-Thr-Val-Glu-Gly-Ala-Gly-Ser-Ile-Ala-Ala-Ala-Thr-Gly-Phe-Val-OH
序列（单字母）：EQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFV
类似名：NAC, α-Synuclein (61-95) (human), Non-β-Amyloid Component of Alzheimer´s Disease (NAC), Non-Aβ Component of Alzheimer´s Disease Amyloid
分子式：C₁₄₁H₂₃₅N₃₉O₄₉
分子量：3260.65
CAS#：154040-19-4
合成方法：固相合成
存储条件：-20 ± 5 °C，避光，干燥
应用：Alzheimer´s Disease Parkinson’s Disease
描述：The 35 amino acid peptide NAC (α-synuclein (61-95)) has originally been isolated from the insoluble core of Alzheimer´s disease (AD) amyloid plaque. The sequence corresponds to a fragment of a 140 amino acid precursor known as NACP or α-synuclein and was found to form amyloid fibrils via a nucleation-dependent polymerization mechanism. Accumulation of NAC aggregates in the synapse might be responsible for the neurodegeneration in AD and in the prion diseases.