产品详情
Cat#: 114P02
序列(三字母):H-Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH
序列(单字母):QRPRLSHKGPMPF
分子式:C₆₉H₁₁₁N₂₃O₁₆S
分子量:1550.85
CAS#:217082-58-1
合成方法:固相合成
存储条件:-20 ± 5 °C,避光,干燥
应用:Obesity Research
描述:Apelin-13, generated from apelin-36, is an endogenous peptide ligand for the human APJ receptor, a putative receptor protein related to the angiotensin receptor (AT1). Apelin-13 exerted an acidification-rate-promoting activity in the CHO cells expressing the APJ receptor with a median effective concentration (EC₅₀) value of 0.37 nM. In a study of Valle et al. chronic central administration of apelin-13 over 10 days increased food intake, body weight, locomotor activity and body temperature in C57BL/6 mice.
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