Cat#: 123P66
序列（三字母）：Z-Val-Ala-DL-Asp-fluoromethylketone
序列（单字母）：Z-VAD-FMK
分子式：C₂₁H₂₈FN₃O₇
分子量：453.47
CAS#：220644-02-0
合成方法：Synthetic
存储条件：-20 ± 5 °C
应用：Apoptosis & Necrosis| Cancer Research
描述：zVAD-FMK inhibited apoptosis induced by diverse stimuli. Preincubation of cells with this caspase-1 (ICE) inhibitor (50 µM) almost completely inhibited the formation of large kilobase-pair fragments of DNA, a characteristic biochemical change associated with apoptosis. Z-VAD-FMK was shown to irreversibly inhibit most types of caspases, hence it is also called pan-caspase inhibitor. Inhibitor of peptide:N-glycanase (PNGase).