产品详情
Cat#: 101P03
序列(三字母):Ac-Ala-Met-Val-Ser-Glu-Phe-Leu-Lys-Gln-Ala-Trp-Phe-Ile-Glu-Asn-Glu-Glu-Gln-Glu-Tyr-Val-Gln-Thr-Val-Lys-OH
序列(单字母):Ac-AMVSEFLKQAWFIENEEQEYVQTVK
类似名:Annexin-1 (2-26) (human), Lipocortin-1 (2-26), Calpactin II (1-25) (dephosphorylated) (human), Ac2-26
分子式:C₁₄₁H₂₁₀N₃₂O₄₄S
分子量:3089.47
CAS#:151988-33-9
合成方法:固相合成
存储条件:-20 ± 5 °C,避光,干燥
应用:Cancer Research
Cardiovascular System & Diseases
Inflammation Research
描述:Annexin A1 (AnxA1) N-terminal-derived peptide, also known as Ac2-26, mimics the antiinflammatory effects of AnxA1. Ac2-26 can activate all three formyl peptide receptor family members FPR, FPR-like (FPRL)1 and FPRL2 at similar concentations. It represents the first endogenous ligand for FPRL2. In myocardial ischemia-reperfusion injury experiments the peptide showed cardioprotective effects. Understanding the underlying mechanism may help developing novel therapeutics for acute cardioprotection.
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