Cat#：131P07
序列（三字母）：H-Ile-Ser-Leu-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Glu-Val-Leu-Glu-Met-Ala-Arg-Ala-Glu-Gln-Leu-Ala-Gln-Gln-Ala-His-Ser-OH
序列（单字母）：ISLDLTFHLLREVLEMARAEQLAQQAHS
分子式：C₁₄₁H₂₃₁N₄₁O₄₃S
分子量：3220.7
CAS#：120066-38-8
合成方法：Synthetic
存储条件：-20 ± 5 °C
应用：Alzheimer´s Disease
描述：This CRF fragment may have two different beneficial effects in Alzheimer´s disease (AD). First CRF (6-33) dissociates CRF from the CRF-binding protein and may therefore be able to restore the dramatic reduction of free CRF content in AD. Second this fragment shows cognition-enhancing properties in animal models of learning and memory, without the characteristic anxiogenic effects of CRF receptor agonists, and may therefore be useful in the treatment of memory deficits seen in AD.