产品详情
Cat#:132P05
序列(三字母):H-Glu-Val-Glu-Asp-Pro-Gln-Val-Pro-Gln-Leu-Glu-Leu-Gly-Gly-Gly-Pro-Glu-Ala-Gly-Asp-Leu-Gln-Thr-Leu-Ala-Leu-Glu-Val-Ala-Arg-Gln-OH trifluoroacetate salt
序列(单字母):EVEDPQVPQLELGGGPEAGDLQTLALEVARQ
类似名:Insulin 1 Precursor (57-87) (rat), Preproinsulin 1 (57-87) (rat), Proinsulin 1 (33-63) (rat)
分子式:C₁₄₀H₂₂₈N₃₈O₅₁
分子量:3259.58
CAS#:41475-27-8
合成方法:Synthetic
存储条件:-20 ± 5 °C
应用:Diabetes
描述:Studies of the cellular effects of C-peptide have shown that it binds specifically in a nanomolar concentration range to a G-protein coupled membrane receptor, with subsequent activation of Ca²⁺-dependent intracellular signaling pathways. This resulted in stimulation of both Na⁺-K⁺-ATPase, and endothelial nitric oxide synthase activities. Administration of C-peptide to streptozotocin induced diabetic rats elicited a substantial increase in whole-body glucose turnover.
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