产品详情
Cat#: 101P09
序列(三字母):H-Leu-Arg-Ala-His-Ala-Val-Asp-Val-Asn-Gly-NH₂
序列(单字母):LRAHAVDVNG-NH₂
类似名:Cadherin-1 (76-85) amide (chicken), N-Cadherin (76-85) amide (chicken), Cadherin Peptide, avian
分子式:C₄₄H₇₅N₁₇O₁₃
分子量:1050.19
CAS#:127650-08-2
合成方法:固相合成
存储条件:-20 ± 5 °C,避光,干燥
应用:Adhesion Molecules & Extracellular Matrix Proteins
Cell Culture
Regenerative Medicine
描述:This decapeptide resides within the first extracellular domain (EC1) of N-cadherin. It inhibits cadherin-mediated cell adhesion, compaction of eight-cell-stage mouse embryos and rat neurite outgrowth on astrocytes. In the presence of this peptide Ca²⁺-dependent cell aggregation of bovine brain microvessel endothelial cells is prevented. A putative application in creating channels for paracellular drug delivery across blood brain barriers has been proposed.
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