产品详情
Cat#: 101P12
序列(三字母):H-Pro-Gly-Pro-OH
序列(单字母):PGP
分子式:C₁₂H₁₉N₃O₄
分子量:269.3
CAS#:7561-51-5
合成方法:固相合成
存储条件:-20 ± 5 °C,避光,干燥
应用:Adhesion Molecules & Extracellular Matrix Proteins
Di- and Tripeptides
Regenerative Medicine
描述:H-Pro-Gly-Pro-OH (PGP) is a tripeptide generated from the breakdown of extracellular matrix collagen and is specifically chemotactic for neutrophils in vitro and in vivo. N-terminal acetylation of PGP (AcPGP - Bachem product H-6412) can enhance this chemotactic potential. PGP was identified as physiological substrate for the aminopeptidase activity of leukotriene A4 hydrolase. PGP is a biomarker for chronic obstructive pulmonary disease (COPD).
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