Cat#：136P35
序列（三字母）：Ac-Lys-D-Lys-Sar-Glu-OH acetate salt
序列（单字母）：Ac-Kk-Sar-E
类似名：Acetyl-(D-Lys⁸⁹,Sar⁹⁰)-β-Lipotropin (88-91) (human), Acetyl-(D-Lys²⁹,Sar³⁰)-β-Endorphin (28-31) (human)
分子式：C₂₂H₄₀N₆O₈
分子量：516.6
CAS#：81483-91-2
合成方法：Synthetic
存储条件：-20 ± 5 °C
应用：Parkinson’s Disease
描述：This metabolically stable analog of MPF is known as a neurotrophic peptide capable of CNS regeneration. It has been shown to reduce parkinsonian-like behaviour in rats with unilateral lesions of their nigro-striatal pathways. This effect is related to reversal of the mitochondrial damage to the neurons. As a mitochondrial defect is supposed to be the initial step in the genesis of Parkinson´s disease, the peptide may be a very useful tool in the investigation of this disease.